ACMIT has developed and is constantly refining an IOL-Simulator device for psychophysical, subjective tests of new IOL designs without the need of actually implanting an IOL. Several clinical studies have already been performed with the setup to investigate different aspects concerning vision quality and IOL design – mainly of multifocal IOLs (see, for example, [1]).

We offer this IOL-Simulator device to our partners in ophthalmic research as a characterisation / research service including tailored study design and study conduction in cooperation with our scientific partners.




Although IOLs can be characterized in multiple ways by applying pure physical measurements such as dioptric power, MTF, Zernike polynomials, etc., the most critical question about patient satisfaction and individual visual perception (including retinal and neuronal image processing) requires tests involving human individuals. Commonly, this is performed via clinical implantation trials with patient assessment after IOL implantation. Besides ethical concerns one might have related to this standard approach, it is also cost-intensive and, almost more importantly, it does not allow for direct comparison of different lens types.

Contrary to the standard approach, the IOL-Simulator fills a gap and offers the possibility to test different IOL types with relative ease and without risk at several individuals. Without the need for IOL implantation, healthy persons are able to experience a pseudophakic visual impression, simulating the situation after IOL implantation. Thus, a direct comparison of the visual impression obtained from different IOL products and even IOL prototypes in early stages of development can be performed.

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Standard tests for different parameters of interest: Visual acuity (VA) and contrast sensitivity (CS) at different chart distances and at ambient or reduced light levels, as well as VA defocus curves.

More sophisticated test scenarios: comparison between 2 or more IOL types, simultaneous viewing of targets at different distances (“3D Tests”), testing of subjective preferences (“Which IOL do you like more – in which of the presented viewing/daily life situation?” etc.).

Further test scenarios according to custom-specific demands can also be developed: Glare/Halo characterisation, IOL positioning mismatch and tolerance tests (effect of IOL positioning errors and tilt on visual performance and perception).

Currently, multifocal and monofocal posterior chamber IOLs can be tested, and the IOL-Simulator device will be tailored to custom specific lenses and test requirements. Test procedure, study questionnaires, and study conduction will be developed and performed in cooperation with scientific partners of ACMIT.


[1] W. Brezna, K. Lux, N. Dragostinoff, C. Krutzler, N. Plank, R. Tobisch, A. Boltz, G. Garhöfer, R. Told, K. Witkowska, L. Schmetterer, “Psychophysical Vision Simulation of Diffractive Bifocal and Trifocal Intraocular Lenses”, Transl Vis Sci Technol. 2016 Oct 17;5(5):13

[2] H. Liou, N.A.Brennan, „Anatomically accurate, finite model eye for optical modeling.“, J. Opt. Soc. Am. A, No. 14, p. 1684-1695, 1997

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